Knowledge of the arteries mechanical and structural characteristics can improve understanding of their behavior and functions, and help to develop or improve vascular devices, such as intracoronary stents. Even though there are many studies concerning global [1], layer-specific [2] or age-specific [3] mechanical properties of coronary arteries, there is still a need to further investigate mechanics and structure of arteries from different parts of the arterial tree. The aim of the study was to determine mechanical and structural properties of left and right porcine coronary artery, dimensions and changes in structure depending on its location were also evaluated.