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Experimental observations of three-dimensional fatigue crack growth arecompared to numerical predictions from the Boundary Element code BEASY. Fractureanalysis results for a complex geometry specimens are presented with regard to 3Dcrack propagation and mode coupling effects. The specimens under consideration arecracked tension specimens, with a through crack or a quarter circular corner crack thatproceed inclined to the remote loading direction. Mixed mode conditions along thecrack edge are characterised: the stress intensity factors are determined using the crackopening displacement method and the crack growth direction is computed by theminimum strain energy density criterion. Effects of specimen complex geometry, causedby a part-through hole nearby the initial three-dimensional crack, on fracture crackpath are analysed. A satisfactory agreement between numerical and experimental crackgrowth direction and crack growth rates are displayed, both for three-dimensional part-through corner cracks and through the thickness elliptical cracks.