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The aim of the work was to compare different methods of probabilistic assessment of fatigue crack growth (FCG) in specific case of an Al-alloy. Actual FCG data measured in four different specimens of an Al-alloy with fairly reduced homogeneity were evaluated using three differently sophisticated methods of probabilistic assessment, namely (i) assessment on the basis of deterministic integration of FCG dependencies considering statistically evaluated tolerance limits along regression line, (ii) probabilistic assessment using ALIAS HIDA software developed in the framework of a European research and development project, with Monte-Carlo simulations and (iii) highly sophisticated probabilistic assessment according to Lauschmann, published in the past. Estimations performed by the three methods were quite comparable, particularly for not too extreme probability values, between 10 % and 90 %. The examples demonstrate an importance of the use of probabilistic methods in damage tolerance estimations with fatigue cracks.